Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening
Summary. This position document from European and American genetics societies provides recommendations for responsible innovation in prenatal screening using non-invasive prenatal testing (NIPT). The authors argue that while NIPT improves accuracy and safety for detecting common chromosomal abnormalities, expanding screening scope requires rigorous validation and ethical evaluation. They call for governments to regulate prenatal screening as public health programs, ensuring quality counseling, professional education, and equitable access rather than allowing commercial expansion without oversight.
Cite this article
(ASHG), O. B. O. T. E. S. O. H. G. (. A. T. A. S. O. H. G., Dondorp, W., Wert, G. D., Bombard, Y., Bianchi, D. W., Bergmann, C., Borry, P., Chitty, L. S., Fellmann, F., Forzano, F., Hall, A., Henneman, L., Howard, H., Lucassen, A., Ormond, K. E., Peterlin, B., Radojković, D., Rogowski, W., Soller, M., . . . Cornel, M. C.. (2015). Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening. European Journal of Human Genetics. https://doi.org/10.1038/ejhg.2015.57
(ASHG), on behalf of the European Society of Human Genetics (ESHG) and the American Society of Human Genetics, et al. “Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening.” European Journal of Human Genetics, 2015. https://doi.org/10.1038/ejhg.2015.57.
(ASHG), on behalf of the European Society of Human Genetics (ESHG) and the American Society of Human Genetics, Wybo Dondorp, Guido de Wert, Yvonne Bombard, Diana W. Bianchi, Carsten Bergmann, Pascal Borry, et al.. 2015. “Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening.” European Journal of Human Genetics. https://doi.org/10.1038/ejhg.2015.57.
@article{ashg-2015-non-invasive-prenatal-testing-aneuploidy,
title = {Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening},
author = {on behalf of the European Society of Human Genetics (ESHG) and the American Society of Human Genetics (ASHG) and Wybo Dondorp and Guido de Wert and Yvonne Bombard and Diana W. Bianchi and Carsten Bergmann and Pascal Borry and Lyn S. Chitty and Florence Fellmann and Francesca Forzano and Alison Hall and Lidewij Henneman and Heidi Howard and Anneke Lucassen and Kelly E. Ormond and Borut Peterlin and Dragica Radojković and Wolf Rogowski and Maria Soller and Aad Tibben and Lisbeth Tranebjærg and Carla van El and Martina C. Cornel},
journal = {European Journal of Human Genetics},
year = {2015},
doi = {10.1038/ejhg.2015.57},
url = {https://doi.org/10.1038/ejhg.2015.57}
}
TY - JOUR TI - Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening AU - on behalf of the European Society of Human Genetics (ESHG) and the American Society of Human Genetics (ASHG) AU - Wybo Dondorp AU - Guido de Wert AU - Yvonne Bombard AU - Diana W. Bianchi AU - Carsten Bergmann AU - Pascal Borry AU - Lyn S. Chitty AU - Florence Fellmann AU - Francesca Forzano AU - Alison Hall AU - Lidewij Henneman AU - Heidi Howard AU - Anneke Lucassen AU - Kelly E. Ormond AU - Borut Peterlin AU - Dragica Radojković AU - Wolf Rogowski AU - Maria Soller AU - Aad Tibben AU - Lisbeth Tranebjærg AU - Carla van El AU - Martina C. Cornel JO - European Journal of Human Genetics PY - 2015 DO - 10.1038/ejhg.2015.57 UR - https://doi.org/10.1038/ejhg.2015.57 ER -
Details
- DOI
- 10.1038/ejhg.2015.57
- Countries
- United States, European Union
- Regions
- North America
- Categories
- policy, innovation-theory, general-innovation
- Added
- 2026-04-28