Decentralized clinical trials in the trial innovation network: Value, strategies, and lessons learned

Daniel F. Hanley, Gordon R. Bernard, Consuelo H. Wilkins, Harry P. Selker, Jamie P. Dwyer, Jay B. Dean, Daniel K. Benjamin, Sarah E. Dunsmore, Salina P. Waddy, Kenneth L. Wiley, Marisha E. Palm, W. Andrew Mould, Daniel E. Ford, Jeri Burr, Jacqueline Huvane, Karen Lane, Lori Poole, Terri Edwards, Nan Kennedy, Leslie R. Boone, Jasmine Bell, Emily S. Serdoz, Loretta M. Byrne, Paul A. Harris · 2023 · Journal of Clinical and Translational Science

Summary. The Trial Innovation Network evaluated decentralized clinical trial approaches across over 400 studies, finding that remote tools like electronic consent, social media recruitment, and remote interventions improve efficiency and reduce participation barriers. Some elements work well, while remote recruitment and monitoring need refinement. Hybrid trials combining remote and in-person methods offer promise for increasing urban-rural diversity, though ensuring equitable access to technology and building trust with marginalized communities remain critical challenges.

Read the original

Cite this article

Hanley, D. F., Bernard, G. R., Wilkins, C. H., Selker, H. P., Dwyer, J. P., Dean, J. B., Benjamin, D. K., Dunsmore, S. E., Waddy, S. P., Wiley, K. L., Palm, M. E., Mould, W. A., Ford, D. E., Burr, J., Huvane, J., Lane, K., Poole, L., Edwards, T., Kennedy, N., . . . Harris, P. A.. (2023). Decentralized clinical trials in the trial innovation network: Value, strategies, and lessons learned. Journal of Clinical and Translational Science. https://doi.org/10.1017/cts.2023.597

@article{hanley-2023-decentralized-clinical-trials-trial-innovation,
  title   = {Decentralized clinical trials in the trial innovation network: Value, strategies, and lessons learned},
  author  = {Daniel F. Hanley and Gordon R. Bernard and Consuelo H. Wilkins and Harry P. Selker and Jamie P. Dwyer and Jay B. Dean and Daniel K. Benjamin and Sarah E. Dunsmore and Salina P. Waddy and Kenneth L. Wiley and Marisha E. Palm and W. Andrew Mould and Daniel E. Ford and Jeri Burr and Jacqueline Huvane and Karen Lane and Lori Poole and Terri Edwards and Nan Kennedy and Leslie R. Boone and Jasmine Bell and Emily S. Serdoz and Loretta M. Byrne and Paul A. Harris},
  journal = {Journal of Clinical and Translational Science},
  year    = {2023},
  doi     = {10.1017/cts.2023.597},
  url     = {https://doi.org/10.1017/cts.2023.597}
}

TY  - JOUR
TI  - Decentralized clinical trials in the trial innovation network: Value, strategies, and lessons learned
AU  - Daniel F. Hanley
AU  - Gordon R. Bernard
AU  - Consuelo H. Wilkins
AU  - Harry P. Selker
AU  - Jamie P. Dwyer
AU  - Jay B. Dean
AU  - Daniel K. Benjamin
AU  - Sarah E. Dunsmore
AU  - Salina P. Waddy
AU  - Kenneth L. Wiley
AU  - Marisha E. Palm
AU  - W. Andrew Mould
AU  - Daniel E. Ford
AU  - Jeri Burr
AU  - Jacqueline Huvane
AU  - Karen Lane
AU  - Lori Poole
AU  - Terri Edwards
AU  - Nan Kennedy
AU  - Leslie R. Boone
AU  - Jasmine Bell
AU  - Emily S. Serdoz
AU  - Loretta M. Byrne
AU  - Paul A. Harris
JO  - Journal of Clinical and Translational Science
PY  - 2023
DO  - 10.1017/cts.2023.597
UR  - https://doi.org/10.1017/cts.2023.597
ER  -

Details

DOI: 10.1017/cts.2023.597
Countries: United States
Regions: North America
Categories: rural-healthcare, broadband-and-digital, general-innovation
Added: 2026-04-28