Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE
Summary. This paper examines responsible innovation in human germline gene editing across Europe. The authors review scientific developments, legal regulations, and ethical considerations for gene editing in basic research, pre-clinical work, and clinical applications. They argue that deontological objections to gene editing lack conviction, while consequentialist concerns about safety require further research. The paper supports adapting regulations to technological progress while addressing ethical and societal concerns.
Cite this article
Wert, G. D., Heindryckx, B., Pennings, G., Clarke, A., Eichenlaub-Ritter, U., El, C. V., Forzano, F., Goddijn, M., Howard, H., Radojković, D., Rial‐Sebbag, E., Dondorp, W., Tarlatzis, B. C., Cornel, M. C., & Embryology, O. B. O. T. E. S. O. H. G. A. T. E. S. O. H. R. A.. (2018). Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE. European Journal of Human Genetics. https://doi.org/10.1038/s41431-017-0077-z
Wert, Guido de, et al. “Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE.” European Journal of Human Genetics, 2018. https://doi.org/10.1038/s41431-017-0077-z.
Wert, Guido de, Björn Heindryckx, Guido Pennings, Angus Clarke, Ursula Eichenlaub-Ritter, Carla van El, Francesca Forzano, et al.. 2018. “Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE.” European Journal of Human Genetics. https://doi.org/10.1038/s41431-017-0077-z.
@article{wert-2018-responsible-innovation-human-germline-gene,
title = {Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE},
author = {Guido de Wert and Björn Heindryckx and Guido Pennings and Angus Clarke and Ursula Eichenlaub-Ritter and Carla van El and Francesca Forzano and Mariëtte Goddijn and Heidi Howard and Dragica Radojković and Emmanuelle Rial‐Sebbag and Wybo Dondorp and Basil C. Tarlatzis and Martina C. Cornel and On behalf of the European Society of Human Genetics and the European Society of Human Reproduction and Embryology},
journal = {European Journal of Human Genetics},
year = {2018},
doi = {10.1038/s41431-017-0077-z},
url = {https://doi.org/10.1038/s41431-017-0077-z}
}
TY - JOUR TI - Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE AU - Guido de Wert AU - Björn Heindryckx AU - Guido Pennings AU - Angus Clarke AU - Ursula Eichenlaub-Ritter AU - Carla van El AU - Francesca Forzano AU - Mariëtte Goddijn AU - Heidi Howard AU - Dragica Radojković AU - Emmanuelle Rial‐Sebbag AU - Wybo Dondorp AU - Basil C. Tarlatzis AU - Martina C. Cornel AU - On behalf of the European Society of Human Genetics and the European Society of Human Reproduction and Embryology JO - European Journal of Human Genetics PY - 2018 DO - 10.1038/s41431-017-0077-z UR - https://doi.org/10.1038/s41431-017-0077-z ER -
Details
- DOI
- 10.1038/s41431-017-0077-z
- Countries
- Belgium, United Kingdom, Germany, Netherlands, France, Greece
- Regions
- Europe
- Categories
- policy, innovation-theory, general-innovation
- Added
- 2026-04-28