Innovation in SPR-based molecular fishing: development and applications of an indigenous Chinese platform

Yang Zi, Wendan Chu, Yukai Ma, Jun Lan, Weihua Wang, Bin Zhou, Mengyun Shi, Biao Wang, Qing Chang, Wenqi Li · 2026 · Biophysics Reports

Summary. Chinese researchers developed and validated a surface plasmon resonance (SPR) instrument called MI-S200F for molecular fishing—isolating target molecules from biological samples. Testing showed the MI-S200F outperformed competing systems in capture efficiency and purity, recovering target molecules at rates 25 times higher than comparable instruments. The platform successfully isolated both proteins and small molecules from complex biological samples with high specificity, demonstrating that Chinese-manufactured bioanalytical equipment can compete with established international instruments.

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@article{zi-2026-innovation-spr-based-molecular-fishing,
  title   = {Innovation in SPR-based molecular fishing: development and applications of an indigenous Chinese platform},
  author  = {Yang Zi and Wendan Chu and Yukai Ma and Jun Lan and Weihua Wang and Bin Zhou and Mengyun Shi and Biao Wang and Qing Chang and Wenqi Li},
  journal = {Biophysics Reports},
  year    = {2026},
  doi     = {10.52601/bpr.2026.260002},
  url     = {https://doi.org/10.52601/bpr.2026.260002}
}

TY  - JOUR
TI  - Innovation in SPR-based molecular fishing: development and applications of an indigenous Chinese platform
AU  - Yang Zi
AU  - Wendan Chu
AU  - Yukai Ma
AU  - Jun Lan
AU  - Weihua Wang
AU  - Bin Zhou
AU  - Mengyun Shi
AU  - Biao Wang
AU  - Qing Chang
AU  - Wenqi Li
JO  - Biophysics Reports
PY  - 2026
DO  - 10.52601/bpr.2026.260002
UR  - https://doi.org/10.52601/bpr.2026.260002
ER  - 

Details

DOI

10.52601/bpr.2026.260002

Countries

China

Regions

Asia

Categories

agtech, innovation-networks, general-innovation

Added

2026-09-01